Newborn Behavioral Effect of Cocaine: Is It Amount of Prenatal Exposure or Acute Toxicity? † 1234
نویسندگان
چکیده
منابع مشابه
Neonatal behavioral toxicity in rats following prenatal exposure to methanol.
Although methanol (MEOH) may assume a significant role as a fuel, which implies wide availability, little is known of its toxicity apart from acute poisoning episodes in human adults. Even less is known about its toxicity in developing organisms. This experiment studied the early behavioral development of rats whose mothers had consumed MEOH during gestation by measuring the responses of suckli...
متن کاملThird pathophysiology of prenatal cocaine exposure.
The pathophysiology of the effects of cocaine on fetal development has been described along 2 major pathways: neurochemical effects and vasoconstrictive effects. Following a summary of these effects, we suggest a 'third pathophysiology' in which altered fetal programming affects the acute and long-term adverse effects of in utero cocaine exposure. We describe how cocaine as a stressor alters th...
متن کاملThe Effects of Prenatal Cocaine Exposure
U.S. Sentencing Commission regarding Drug Penalties (Feb. 25, 2002) at 2. “[T]he home environment is the critical determinant of the child’s ultimate outcome. . . . The drug-exposed child most often comes from a neglectful family lifestyle filled with factors that interfere with the parents’ attempts at effective child rearing and participation in the growth and development of their children. ....
متن کاملMechanisms of acute cocaine toxicity.
Patients with acute cocaine poisoning present with life-threatening symptoms involving several organ systems. While the effects of cocaine are myriad, they are the result of a limited number of cocaine-protein interactions, including monoamine transporters, neurotransmitter receptors and voltage-gated ion channels. These primary interactions trigger a cascade of events that ultimately produce t...
متن کاملThe normal newborn exam, or is it?
Despite the broad technologic advancements of medicine, screening for illness in infants is highly reliant on a complete physical exam. For this reason it is critical that the examining physician not only have a thorough understanding of abnormal findings but also the normal findings and their variants. The vast majority of infants are healthy and findings predictive of future health problems a...
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ژورنال
عنوان ژورنال: Pediatric Research
سال: 1998
ISSN: 0031-3998,1530-0447
DOI: 10.1203/00006450-199804001-01255